A steroid as potent as testosterone suspension has more side effects compared with its esterized counterparts. Users report increased water retention and bloating as some of the effects they experienced while using the steroid. Some also observed fat gain during their cycles.

High rates of acne, water retention, and aromatization are possible while using testosterone suspension. Increased blood pressure and liver toxicity are normally not an issue unless dosages are very high. The reason for that being because the liver is already accustomed to processing testosterone. Testosterone suspension readily converts to DHT and significantly suppresses HPTA function. As a result, the user should be familiar with a host of ancillary drugs included anti-estrogens such as Nolvadex and Clomid as well as HCG which may be beneficial to run during cycle to prevent the suppression of HPTA and decrease the length of time required to achieve normalization post cycle. Generally speaking, natural testosterone production should return to normal post cycle whether or not HCG is used, but HCG is known to dramatically decrease the length of time required to see this normalization take place.

Even those women who run low doses of testosterone will likely find it unnecessary to venture into attempting a cycle of testosterone suspension. Due to the frequent injection schedule that the compound requires, and the low doses that most women run when cycling testosterone, it become counterproductive to be shooting such a small amount of a compound so frequently when other more convenient drugs are available. However, if a female does attempt to run testosterone suspension, the usual virilizing side effects would be expected.